Centrifuge – The most popular Laboratory device

A centrifuge is one of the most popular laboratory devices around. Almost every chemical and medical laboratory will have one, besides which several other laboratories also have a centrifuge. The Laboratory Centrifuge There are many applications of a centrifuge device. It has medical applications like helps in the analysis of blood, it has chemical applications, like help in the analysis of several chemicals. A centrifuge is also used space station laboratories for testing purposes. A laboratory centrifuge is a device that is driven by a motor that spins the liquid sample at a very high speed. The size of the centrifuge can vary, depending on the size of the sample. Such centrifuges come with a speed setting as well. The basic principal of a centrifuge is the sedimentation effect, where centripetal acceleration is used to separate greater and lesser density substances.

What is a centrifuge used for in a lab?

A centrifuge is a very useful device in the laboratory. There are many applications for this device. It is used in the separation of fluids, gas and other liquids based on their respective density. The way it works is by spinning the sample at a very high speed in the centrifuge and allowing the centripetal force to separate the heavier particles to the outer section of the centrifuge. Here is a list of applications of a centrifuge in a laboratory:

• The centrifuge is used to separate a blood sample into different components. This separation helps in the analysis of the various components of blood like, red blood cells, white blood cells, plasma, etc.

• A centrifuge is used in DNA / RNA separation. It is also used for cell culture separation.

• Besides which it is also used in the study of viruses, proteins, nucleic acids, polymers, and blood.

Neuation has the perfect centrifuge for you

Neuation manufactures many laboratory equipments including the centrifuge. Neuation is an ISO 9001: 2008 company hence their products are of high quality. In addition, to which the management system is ISO 13485: 2003 (certified lab equipment manufacturer). All their products are consistently good and of international quality. A great deal of research is done at Neuation to improve the existing products and experiment with new ones. Hence the centrifuge devices available here are highly feature rich and of high quality.

What Are A Centrifuge And The Theory Behind It

A centrifuge is basically a machine that spins around to create a force. It has many practical purposes like to separate blood products which help in the analysis of the blood. It also has many other practical applications in aerospace labs where huge centrifuges are used for testing the endurance of space equipment.

How do Centrifuges Work?

A centrifuge works on the basic principle of the force that is generated when you spin something. For example, when sitting in a merry go round while spinning at high speed you will feel a force that hurls you out of your seats but you still remain in your seat. This is an invisible force and is also the basis of how a centrifuge works. The fact of the matter is that this invisible force so to speak is called centripetal force. The basic principle behind the working of a centrifuge is the fact that denser substances and particles move towards the outward direction due to the centripetal acceleration. This also causes the less dense objects to move the center. The centripetal force is the force that acts on a moving body that is moving in a circular path and is directed towards the center of the body in motion.

What do Centrifuges do?

Centrifuges are used for scientific purposes in several chemical laboratories. It is thus possible to separate red blood cells suspended in blood plasma. Thus if a test-tube with a blood sample is placed in a centrifuge, you will find that the plasma is suspended at the top and the red blood cells at the bottom. What are centrifuges used for? Centrifuges are commonly used chemical and medical laboratories around the world. It has the ability to spin the sample at high speeds. A sample is usually placed inside the centrifuge with a tight latch to keep the lid in place. When in operation, this device spins at high speeds causing vibration and at times can be displaced by the force too. Hence the centrifuge needs to be placed in a sturdy place.

Neuation Has the Perfect Centrifuge For You

Neuation centrifuge manufacturers offer many laboratory equipments including the centrifuge. They are an ISO 9001: 2008 company hence their products are of high quality. In addition, to which the management system is ISO 13485: 2003 (certified lab equipment manufacturer). All their products are consistently good and of international quality. All products sold by Neuation are a result of extensive research and development.

Definition and Functioning of Clinical Centrifuge

Clinical Centrifuge Definition

Clinical centrifuge machines are the most basic machineries in any clinic. These equipment are used to test liquid found inside the living being. It separates plasma from the blood. It rotates on the axis on fixed density, sometimes 1500 RPM in one minute. The timer button is given on the equipment. The person who is performing the test sets the timer as per the test requirement.

Basically, how does clinical centrifuge functions?

It is a small equipment, and can be found in any biotechnology school and college lab. This machine is fixed on the axis which rotates in high speed in the same location and in the same speed. The laboratory person inserts the liquid in the tube and places a cap on it. The tubes can be of either plastic or glass. The capacity of the tubes vary from 10 ml to 100 ml. Then he or she inserts the tube in the equipment and shuts it. Timer is set with the required RPM. It works on the sedimentation principle where parts of water are separated (if you remember the chapter of sedimentation studied in the school). The same way particles are separated. The heavy density particles stays in the bottom and the light weighted comes up.

As per the need and requirement these following types of centrifuge can be used;

1. Micro Centrifuge
2. General purpose centrifuge
3. Large capacity
4. Super speed

Clinical Centrifuge Use

However, the type of fluid separation depends up on the density. And the density is determined by the type of centrifuge. When we say separation it means, separating plasma from the blood, protein from the fluid, other solid particles from the fluid. It also separates sediments from the urine. Such tests determine the type of disease in the living being.

Beside, density and timer there is a button called temperature. Different different tests require varied temperature, some require less and some require high.

These are the most common tests happen in the clinical centrifuge laboratory. It was earlier used to separate DNA from the blood, but now there are more advance technologies available for separating the DNA, and thus it is less popular in the centrifuge lab.

Training of Operation

The equipment comes with in-build safeguards. It is recommended to the laboratory operators to clean all the equipment in the lab twice a year.

Balancing of tubes is very important during the run. Make sure all the tubes are placed in front of each other to avoid unbalancing.

If, in case, equipment require extensive and frequent services, it is better to replace.

Introducing Neuation

Neuation offers new generation laboratory equipment like clinical centrifuge. It is an ISO 9001:2008 & iSO 13485:2003 certified company. It fulfills CE standards to supply all the products in the international market. It offers iFuge D06;

• It has a brushless motor
• Less maintenance
• Suitable for PPP (platelet poor plasma) and PRP (platelet rich plasma)
• Suitable for other diagnostic applications in the clinical or research laboratory

To know more, visit http://www.neuation.com/doctors-centrifuges.html

Everything That You Need To Know About Micro-Centrifuge Equipment

What is Micro-centrifuge?

They are same as the Centrifuge, the only thing is that they carry lesser amount of fluid to test-maximum 2 ml or lesser than that. The liquid samples inserted in the tube spin at a very high speed.

So, what does a micro-centrifuge do?

The main reason they are used is to centrifuge nucleic acid and protein. When we say nucleic acid and protein, it means DNA and RNA. These tests are run in molecule laboratory. Amongst other clinical laboratory it is used excessively in molecule biology section. The samples tested here are very small in quantity, but the big research depends on these quantity only. These tests are performed using Eppendorf tubes. These tubes are specifically made for molecular labs only. These tubes are used in PCR laboratories as well.

Understanding Functions

Tubes

The tubes inserted in the equipment are small in size. They are built up of plastic, and they are supposed to discard after one use. They are cylindrical in shape. The tubes have different sizes as per the fluid quantity. They come in 0.5 ml, 1.5 ml, 0.2 ml and 2 ml size. The most common tube size is 1.5ml. Disinfection of the tube is possible, but due to small size they are difficult to clean, but inexpensive. So it is better to purchase new one.

Equipment

The maximum speed of this equipment is 13000 to 15000 RPM (round per minute). The equipment has a button that allows you to set the speed. Alike, centrifuge equipment the balancing of tubes is important-technically it is called sample loading balancing. By balancing we also mean that the quantity we are inserting in one tube should be similar in remaining tubes. Which means if one tube has 1.5 ml fluid, other tubes must consist around same quantity. Sometimes it is seen that the laboratory person has only one sample to test. In that case he can insert water or oil of the same density of the sample in other tubes and run the test.

Rotor

There are two types of rotor;

• Fixed Angle Rotor
• Swinging Bucket Rotor

The rotor lids come in two types, one is plastic which is helpful in avoiding corrosions and are transparent. Second is built up of steel which is easy to use and much safer. Both have their own advantages, however, metal rotor lids are recommended.

Safety Measures

Sometimes during the test, the equipment starts vibrating. To avoid such cases try to keep surface in level.

Introducing Neuation

Neuation offers a wide range of next generation microcentrifuges for various applications in research labs for processing low volume samples.

• Highly efficient
• Smart
• Best work for biotech/PCR work, DNA/RNA extractions
• Speeds up to 15000 rpm.

The available models are, iFuge M08, iFuge BL08 VT, iFuge M12P, iFuge M18P.

To know more about it, visit the page, http://www.neuation.com/microcentrifuges_new.html

A Guide to Help by the Appropriate Microcentrifuge

All most every medical laboratory will have a Microcentrifuge device; the main reason being that there are many uses of Microcentrifuge device. It is very common for a chemical and biological laboratory to have one too. This is one device that is used to a great extent in such labs and for many other applications as well.

Since a Microcentrifuge is so commonly used, there are several types of them available. This article goes on to explain the subtle differences and special choices that you can make when need to buy centrifuge.

The Tube:

A Microcentrifuge can be used with a wide range of tubes. The tubes are usually special purpose ones and then there are also those for general purpose.

Here are a few tips that may come handy when selecting a tube:

• It is important to first make a note of the type of samples that will be used with the microcentrifuge, since different samples have different requirements.

• The tubes themselves can be straight or curved walled. They can also be with screw tops or pop tops.

• Their size can also vary like 0.5ml or 0.4 ml or even 0.2 ml. These are the small sized tubes and will usually require an adapter to fit in the rotor’s holes.

• The normal sized tubes can be like 5ml and even upto 50ml.

• Furthermore, there are several other special purpose tubes ls, like cryotubes, HPLC tubes, PCR strips, mcrotiter plates and hematocrits also called capillary tubes.

• The rotor essentially dictates the type of tube that can be used with the mircocentrifuge. However, you do have the option of switching between rotors in some microcentrifuge devices, but not all of them.

Rotor Specifications:

• The capacity of the rotors also vary. The capacity of the rotors can range from 24, to 30 and evey 48 standard size tubes.

• The rotors can also be special purpose ones to deal with the tubes that contain toxic substances. Rotors with special PTFE (Teflon) coating are available for high chemical resistance.

• The other type of rotor is the swinging bucket rotor. This one is good for density gradient centrifugation and size separation.

• The rotors also have a speed setting and different rotors have the ability to rotate at different speeds. Each rotor will usually have a rating which dictates the speed at which they can be rotated. There are also special safety settings that prevent the rotors from rotating any faster. For example, the 48 tube rotor has a lower rating than the 24 tube rotor.

Neuation’s Centrifuge Devices:

Neuation is leading the way in the development of microcentrifuge devices. In fact they manufacture several laboratory equipment and devices. They are experts in developing new and innovative products to suite the requirements of people using such devices.

The benefit of choosing the Neuation devices for your laboratory needs is that their devices are functionally and aesthetically sound. Since they develop several laboratory equipment and also have a research division, their devices are very efficient, fast, keeping with the technological changes and above safe to use.