Definition and Functioning of Clinical Centrifuge

Clinical Centrifuge Definition

Clinical centrifuge machines are the most basic machineries in any clinic. These equipment are used to test liquid found inside the living being. It separates plasma from the blood. It rotates on the axis on fixed density, sometimes 1500 RPM in one minute. The timer button is given on the equipment. The person who is performing the test sets the timer as per the test requirement.

Basically, how does clinical centrifuge functions?

It is a small equipment, and can be found in any biotechnology school and college lab. This machine is fixed on the axis which rotates in high speed in the same location and in the same speed. The laboratory person inserts the liquid in the tube and places a cap on it. The tubes can be of either plastic or glass. The capacity of the tubes vary from 10 ml to 100 ml. Then he or she inserts the tube in the equipment and shuts it. Timer is set with the required RPM. It works on the sedimentation principle where parts of water are separated (if you remember the chapter of sedimentation studied in the school). The same way particles are separated. The heavy density particles stays in the bottom and the light weighted comes up.

As per the need and requirement these following types of centrifuge can be used;

1. Micro Centrifuge
2. General purpose centrifuge
3. Large capacity
4. Super speed

Clinical Centrifuge UseDoctor Clinical Centrifuge

However, the type of fluid separation depends up on the density. And the density is determined by the type of centrifuge. When we say separation it means, separating plasma from the blood, protein from the fluid, other solid particles from the fluid. It also separates sediments from the urine. Such tests determine the type of disease in the living being.

Beside, density and timer there is a button called temperature. Different different tests require varied temperature, some require less and some require high.

These are the most common tests happen in the clinical centrifuge laboratory. It was earlier used to separate DNA from the blood, but now there are more advance technologies available for separating the DNA, and thus it is less popular in the centrifuge lab.

Training of Operation

The equipment comes with in-build safeguards. It is recommended to the laboratory operators to clean all the equipment in the lab twice a year.

Balancing of tubes is very important during the run. Make sure all the tubes are placed in front of each other to avoid unbalancing.

If, in case, equipment require extensive and frequent services, it is better to replace.

Introducing NeuationNeuation offers Doctor Centrifuge

Neuation offers new generation laboratory equipment like clinical centrifuge. It is an ISO 9001:2008 & iSO 13485:2003 certified company. It fulfills CE standards to supply all the products in the international market. It offers iFuge D06;

  • It has a brushless motor
  • Less maintenance
  • Suitable for PPP (platelet poor plasma) and PRP (platelet rich plasma)
  • Suitable for other diagnostic applications in the clinical or research laboratory

To know more, visit http://www.neuation.com/doctors-centrifuges.html

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There is More to Centrifuge Rotors That You Should be Aware Off

A centrifuge device can be found in several kinds of laboratories. It is quite commonly used in the field of medicine and hence all most every medical laboratory is likely to have one. It is capable of high speed rotation which is very useful in many areas of research.

The centrifuge rotation speed can be as high as 20,000 RPMs to even 40,000 RPM. In fact, it can also go as high as 100,000 RPM. The bioscience laboratories benefit a great deal due to the high speed centrifugation. The bioscience applications include concentrating cells in suspension, separating and isolating cell membranes from cytosolic contents and even purifying and isolating genetic material.

A centrifuge is not a device that is purchased very often and hence it is necessary to be aware of all the facts in order to make the right decision. There are several types of centrifuge rotors where all have a different application. Here are few facts that one should be aware off.

Tips & Facts Concerning Centrifuge Rotors:

Types of centrifuge rotors

  • The rotors can cost quite a bit; their price in terms of dollars range from 100 dollars to may be a few thousand dollars.
  • The cost of a rotor depends on the number of tubes capacity as well the size of the tubes, like either 500ml or 80ml, etc. In addition to which speed capabilities of the rotor also influence the cost.
  • Considering the fact that a good rotor, especially a high speed rotor with additional features can set you back quite large amount of money, it is advisable to make sure you give a good though to the current usages as well as future usages prior to selecting one.
  • It is important to note that the rotors do have a maximum speed specification and the higher the speed capability the higher the cost is likely to be.
  • It is necessary to be aware of the ‘k-factor’. The lower the value of the ‘k-factor’ the better and more efficient is the centrifuge device. A rotor having a lower ‘k-factor’ has the ability to perform its task faster as well. The ‘k-factor’ is based on the geometry of the rotor and the RPM as well.
  • The rotor design depends on the type vessel type being used. It is possible to use tubes, bottles as even microplates in a rotor. Hence if one has a clear picture of the future applications of the rotor and vessel type, it will help them in purchasing the correct one.
  • The centrifuge can be used for several kinds of samples. Some samples may need to be maintained at a low temperature, for example a blood sample, while other samples may be highly toxic. Hence special purpose centrifuges are also available with special purpose rotors.
  • The rotor material also plays an important role. It can be either metal, anodized aluminium or titanium.
  • The rotor configuration plays an important role in achieving efficiency. One of the more common configuration is the fixed angle rotor configuration. This configuration is usually used for pelleting cells.
  • The swinging bucket configuration is also quite popular. This has even spaced holes and the buckets are attached to the rotor by pivots. The buckets have the ability to swing outwards during operation.

Neuation’s Centrifuge Devices

Neuation’s Centrifuge Devices

If you are searching for laboratory centrifuge manufacturer, Neuation is leading the way in the development of several laboratory equipment and devices. They are experts in developing new and innovative products to suite the requirements of people using such devices like the hot plate, a centrifuge, the magnetic stirrer and many more. These devices are often used in a laboratory and for educational purposes.

The benefit of choosing the Neuation devices for your laboratory needs is that their devices are functionally and aesthetically sound. Since they develop several laboratory equipment and also have a research division, their devices are very efficient, fast, keeping with the technological changes and above safe to use.

Hot Plates – The Essential Laboratory Equipment

What are hotplates?What are hotplates?

A hotplate is a highly portable device that can have up to two gas burners. There are two sizes of hotplates available though. One is the single burner and the bigger one and the other is the double burner one. There are two types of burners available too and it can also be a heating element (electric too) for some. The portable one is small enough to be used on the table top as a standalone device. The main feature of hot plate is that it does not require any other resource except electricity to operate.

What is a hot plate used for in the lab?The hot plate is a vital device that is used in a laboratory to heat samples

The hot plate is a vital device that is used in a laboratory to heat samples. The fact that it has the ability to heat the sample without any exposed flames is one of the major advantages. It is a device that can be used on a daily basis for temperatures as high as 100 degrees and even higher.

It is important to check material of the hot plate surface. There is a big advantage of using a flat plate however the hot plate can be made from several materials like ceramic, aluminium or enamel. An aluminium heating plate can distribute the heat evenly and that too quite fast and efficiently. It is a device that is easy to clean and maintain as well. Although care must be taken against corrosion.

The other materials used to make a hot plate are ceramic and enamel. These too have their own unique characteristics. They are both considered to be more durable in terms to handling temperature as well as strong chemicals. These plate can resist higher temperature and are also sensitive to color change. Hence the color change due while heating of plate is more noticeable.

Neuation has the perfect hot plate for you:

Neuation hot plate magnetic stirrer

Neuation offers several laboratory equipment including hot plates. They produce several types of magnetic stirrers including the hot plate magnetic stirrer. Their stirrers are PTFE coated for added protection.

Neuation offer only the best products. They are an ISO 9001: 2008 company hence their products are of high quality. In addition to which the management system is ISO 13485: 2003 (certified lab equipment manufacturer). All their products are consistently good and of international quality.

The main advantage of choosing Neuation is that they also have an R&D division that performs a lot of research and continuous upgrades to their devices.

Centrifuge is the best Laboratory Equipment

Centrifuge is the best Laboratory Equipment

  • When you think of a well equipped laboratory, you cannot disregard centrifuge. Actually, without centrifuge, there is no possibility of a laboratory. That’s why it is always referred as centrifuge laboratory equipment.
  • Since its very much usage in a lab, centrifuge has become an integral part of a laboratory. However, in general, it is most widely used in bio-medical research laboratory all over the world.

Use of Centrifuges in a Lab

Lab Centrifuges

  • As it is laboratory equipment, it is specifically used whenever a researcher needs to separate fluid, gas, or liquid based on density. And the whole process of separation is regarded as centrifugation.
  • By centrifugation, complex components of mixture are separated by its density as per the requirements.
  • If its dense particles, they move towards the bottom while the lighter particles move towards the top.
  • The whole process of centrifugation takes place depending upon its motor. If a motor is of a good quality, it moves at high speed.
  • With the help of centrifuge, one can easily separate blood into its components such as white blood cells, red blood cells, plasma and platelets.
  • As the plasma has the lowest density, it floats on the top while others remain in the bottom as per their density.
  • Most common centrifuges are used in biology, chemistry and biochemistry just to differentiate suspensions. Apart from this, centrifuges are also used in dairies for separating milk.
  • In order to separate cream from milk, milk professionals use centrifuges. With the help of centrifugation, one can easily separate water, soluble, non-soluble fats and other substance from milk.
  • And this whole process of separating mainly depends on motors of centrifuges. Because motor gives speed to the process and one can achieve the desired results through centrifugal.
  • Above all, urinalysis can be done through centrifuges. The doctors can identify possible diseases in humans through urine components. After that lab technicians verify the components through microscopes.
  • Blood banks also use centrifuges for identifying various components in blood in order to judge the existing diseases in patients. Thus, all major laboratories use centrifuges in great extent as per their requirements.

How to choose Laboratory equipment’s?

Laboratory equipment's

  • Research laboratories have become part and parcel of everyday life. Whether you think about food products, chemical products, beauty items, pharmaceuticals, military and many more, one thing is common for all of these is laboratory shaker.
  • All these industries need to research a lot before presenting any of the products to their customers.
  • With the help of research, they can provide authentic and scientific report in order to prove that the product or the report is 100% tested and verified.

Criteria to choose laboratory mixtures:

  • It is important for you to know the basics of choosing laboratory equipment Because, when we talk about mixture or shaker, there are many types of mixtures available in the market like laboratory mixtures, industrial mixtures and specialty mixtures.
  • All these products are manufactured using different components including motors or air, magnets and variable speed controls. But, before you start looking for any of the laboratory equipment; it is important to exactly know the need of laboratory.

Otherwise, a wrong decision can harm more. These following points need to be considered firstly:

  • Power supply source
  • Container capacity
  • Lab requirements for the duty cycles
  • Torque and horsepower needed

Once you are clear about above mentioned points, you can go ahead with the type of container such as shaker, mixture or roller.

  • Though all these products look similar in certain ways, each product has its specific amalgamation process.
  • Scientific shaker uses vibrations along with tilting to complete the mixture of two liquids in order to provide the results in health-care laboratories. While mixtures use blade or small paddles in order to combine the substances.

Moreover, there are some basic features or characteristics that will help you decide which equipment is more suitable to your needs. Here are they:

  • Made using industrial grade
  • Should be light in weight for easy mobility
  • Variable speed should be included
  • Operations should be in continuation without making any noise

Thus, you can select any of the laboratory equipment (shaker, mixture or roller) following above mentioned points and produce desired and quality results in minimum time-frame in your respective fields.

A comprehensive guide on Laboratory Centrifuge Safety

Laboratory-Centrifuge

  • Liquid samples are placed inside the centrifuge device and spun at high speeds in order to separate matter of different densities.
  • This seems like a harmless enough device to operate although like every other laboratory equipment this device too needs has a list of rules as well as dos and don’ts attached to it.
  • This harmless device could very well cause some serious accidents and thus it necessary to make sure that the device is handled by trained professionals and that they are aware of the safety measures; which is what this article is all about.

Safety Measures:

Safety Measures

  • Basic care and maintenance of the laboratory centrifuge is essential to ensure the proper functioning of the laboratory equipment.
  • Regular inspection of the equipment via the daily, monthly and yearly maintenance of the equipment helps make sure that the accidents are avoided.
  • This helps maintain safe working practices in a laboratory.

Here are a few safety measures mentioned to guide you while using a centrifuge device.

  • It is vital that you used the correct kind of glassware.
  • It is necessary use the glassware made from borosilicate glass since common glass can easily break or shatter thus causing damage.
  • It is important to note that different glassware has different implementations and are used for different purposes. For example in case of a laboratory centrifuge test tubes usually contain the sample.
  • The cleaning of the glassware is of utmost importance. Furthermore the faster you clean it after use the easier it is to successfully clean it.
  • Any crack detected in the test tube should not be ignored.
  • The test tubes should be inspected for cracks, chips or scratches in general prior to use and while storing. You need to be extra careful of the so called star cracks that usually form on the bottom of tubes.
  • As a precautionary measure, you should never leave glassware unattended. The basic reason being that the contents of the glassware (test tube) could either be toxin or hot and harmful to an unsuspecting tab technician or cleaner.
  • It thus should be handled and kept by the appropriate centrifuge operator.
  • It is our general instinct not to work bare hands when it come to broken glass. That said you should always ensure that you place all the broken glassware (test tubes, etc) in a box that is clearly marked like “Broken Glassware”., This will go a long way in ensuring the safety of everyone involved.
  • Make sure you do not overfill the test tubes or any other containers for that matter.
  • Make sure that the emergency cut-off switch is working and checked for the same regularly.
  • The electrical cords must be inspected during the maintenance procedures and the area surrounding the laboratory centrifuge must always be kept dry.
  • Make sure you close the centrifuge lid prior to operating it. Additionally most devices have an additional safety feature where the device shuts down if the lid is opened.
  • This feature if exists on you laboratory centrifuge should also be often tested to make sure it is functioning just fine.
  • It is necessary to place the centrifuge on a place surface and additionally it should also be vibration free.
  • It is important to never leave the laboratory centrifuge unattended.
  • Cleanliness is of utmost importance. The rotors and buckets should be kept clean.
  • Some basic checks should be made prior to use like making sure that the rotor is properly seated on the drive shaft.
  • The tube containers are required to be properly balanced in the rotor.
  • It may be possible to set a high speed on the centrifuge though it should never exceed the rotor’s maximum capacity.

Procedures for safe usage of Centrifuge device:

Centrifuge device1

There are several things to keep in mind during each stage of dealing with a laboratory centrifuge as mentioned here:

  • The centrifuge operators should be well trained prior to using the device itself. It is a good practice for them to read the manual too prior to actually using the device.
  • Make sure that you used rotors that are compatible with the centrifuge.
  • The O-ring should be examined to make sure it is not worn off, cracked or missing altogether.
  • It is vital to cap the tubes prior to centrifugation.
  • During the process of centrifugation, if you notice additional noise or vibration then the device should be stopped immediately and checked. This to check in such a situation include the balancing of loads.
  • After the process of centrifugation has come to an end you should allow the centrifuge to come to a complete stop before opening it.
  • Additionally the operator should be wearing gloves while handling the rotor and samples.
  • Again, once the process has been completed you need to check for possible spills and clean the centrifuge if required.
  • In case of dealing with biohazard substances, make sure you label the sample correctly and mention that it is a biohazard.
  • Ideally celluloid tubes should not be used when dealing with biohazard substances.
  • The exterior surface of the tubes should be wiped with disinfectants prior to loading into the rotor.

Thus a laboratory centrifuge may seem like a harmless device which is easy to use and maintain.

The fact is that it is a fairly safe device to use provided you use it correctly and make sure you are aware of all the possible things that can go wrong.

Equipping yourself with the knowledge of safety procedures and measure can go a long way in helping you stay safe and maintain health and safety in the laboratory.

Neuation is one company that designs and develops it’s own products and they are done by its very own R & D team. Thus the products are designed by keeping the safety of the operator and laboratory personnel in mind and are also very good quality and possess a good user interface.

Use of Centrifuge

A centrifuge is used in clinical laboratories extensively. It is essential for the process of separating solids from a liquid suspension. The solids can be of many different types like insoluble cell organelles, compounds or even biomolecules. Centrifugal force is instrumental in analyzing the blood samples and substances of different densities. There are many different kinds of lab centrifuge devices with varying level of technologies to meet the increasing demand for the device.

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It is essential to have a centrifuge device in a clinical laboratory as well as large medical facilities (even small for that matter). They are used for separating substances of varying densities and also for removing chylomicrons. In addition to which they are certain centrifuges with batch rotor for pelleting which do ensure additional features like steroid hormone assays, separating lipoprotein fractions for HDL, LDL and VLDL.

The main features of these centrifuges devices are that they are silent and vibration resistant and also easy to operate. They offer many different features like LED power indicator light, auto off feature, space saving design, angled head rotors, lid with safety interlocks. In addition to which they also sport detachable power cords, easy to clean exterior, timer and on off switch, braking system and speed control knob.

This laboratory equipment also comes equipped with maintenance free brushless motor closed by a safety lid. The lid is instrumental in keeping the chamber from opening when the motor is in use, thus preventing any unwanted hazards. Most of the centrifuges have built in shut down feature if the lid is opened to avoid disasters.

A centrifuge is available in many different specifications and thus it is advisable to purchase it from the correct place by first ensuring the quality of the product. Neuation is a company that design and develop their own user centric, high performance Centrifuge equipment. They have their own R & D team that make all the magic happen and constantly reinvent themselves.

About Author:- Johanna Williams

Johana Williams

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Other laboratory centrifuges related post:

1. How to Centrifuge Blood

2. Advanced Features of Lab Centrifuges

3. Centrifuges: Adding Safety and Versatility to High-Speed Separations

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